Motif ID: TAL1_TCF{3,4,12}.p2

Z-value: 0.912


Transcription factors associated with TAL1_TCF{3,4,12}.p2:

Gene SymbolEntrez IDGene Name
TAL1 6886 T-cell acute lymphocytic leukemia 1
TCF12 6938 transcription factor 12
TCF3 6929 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
TCF4 6925 transcription factor 4



Activity profile for motif TAL1_TCF{3,4,12}.p2.

activity profile for motif TAL1_TCF{3,4,12}.p2


Sorted Z-values histogram for motif TAL1_TCF{3,4,12}.p2

Sorted Z-values for motif TAL1_TCF{3,4,12}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TAL1_TCF{3,4,12}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_14493905 1.341 TRIO
triple functional domain (PTPRF interacting)
chr16_+_4546491 1.065 NM_001145011
LOC342346
hypothetical protein LOC342346
chr19_+_15765760 1.061 NM_001004466
OR10H5
olfactory receptor, family 10, subfamily H, member 5
chr1_+_221168388 1.054 NM_032890
DISP1
dispatched homolog 1 (Drosophila)
chr3_+_196933481 1.006 MUC20
mucin 20, cell surface associated
chr20_+_36643251 0.970 NM_001018082
ADIG
adipogenin
chr1_-_23393808 0.932 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D
chr12_+_63510481 0.928


chr16_-_29817841 0.848 NM_001114099
NM_001114100
NM_012410
NM_201575
SEZ6L2



seizure related 6 homolog (mouse)-like 2



chr8_-_81155564 0.800 NM_001025252
TPD52
tumor protein D52
chr2_-_158008763 0.773 NM_004288
CYTIP
cytohesin 1 interacting protein
chr11_-_68505030 0.754 NM_198923
MRGPRD
MAS-related GPR, member D
chr17_+_38256886 0.739


chr7_-_36992221 0.679 NM_130442
ELMO1
engulfment and cell motility 1
chr10_-_73518772 0.676 NM_001134434
NM_014767
SPOCK2

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2

chr16_+_76613912 0.666 NM_005752
CLEC3A
C-type lectin domain family 3, member A
chr6_-_30188845 0.648 NM_007028
TRIM31
tripartite motif containing 31
chr10_+_5228756 0.627 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr17_+_38256710 0.627 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr7_+_94953148 0.625 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr1_-_156800017 0.619 NM_001160325
OR6P1
olfactory receptor, family 6, subfamily P, member 1
chr7_+_75977680 0.613 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr5_-_134810696 0.609 NM_130848
C5orf20
chromosome 5 open reading frame 20
chr5_-_131907071 0.607 NM_000879
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr17_-_44641741 0.598 NM_031498
NM_001198755
NM_001198756
GNGT2


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2


chr21_+_29439768 0.552 C21orf7
chromosome 21 open reading frame 7
chr12_-_2814410 0.536 NM_031474
NRIP2
nuclear receptor interacting protein 2
chr22_+_38652555 0.532 GRAP2
GRB2-related adaptor protein 2
chr21_+_17841297 0.527 CXADR
coxsackie virus and adenovirus receptor
chr1_-_203657803 0.511 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr5_+_38439399 0.506 NM_182798
NM_182799
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr10_+_85923473 0.500 NM_207373
C10orf99
chromosome 10 open reading frame 99
chr1_+_116181927 0.497 NHLH2
nescient helix loop helix 2
chr1_+_242283129 0.485 NM_006352
ZNF238
zinc finger protein 238
chr11_+_113165134 0.472 LOC390251
SH3-domain GRB2-like 1 pseudogene
chr19_+_4442610 0.471 HDGFRP2
hepatoma-derived growth factor-related protein 2
chr5_-_176258920 0.468 NM_002115
HK3
hexokinase 3 (white cell)
chr1_+_54786394 0.442 NM_015547
NM_147161
ACOT11

acyl-CoA thioesterase 11

chr10_-_49792282 0.421 NM_001006939
LRRC18
leucine rich repeat containing 18
chr1_+_156842852 0.417 NM_001004478
OR10Z1
olfactory receptor, family 10, subfamily Z, member 1
chr15_-_40537002 0.406 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr3_-_196792059 0.403 APOD
apolipoprotein D
chrX_-_46503415 0.400 NM_032591
SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr16_-_70168449 0.391 NM_000353
TAT
tyrosine aminotransferase
chr12_-_121753795 0.390 NM_177551
GPR109A
G protein-coupled receptor 109A
chr3_+_134976965 0.387 TF
transferrin
chr1_-_158948176 0.386 NM_001778
CD48
CD48 molecule
chr21_-_33107813 0.385 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr11_-_62445308 0.382 CHRM1
cholinergic receptor, muscarinic 1
chr9_-_135435165 0.378 NM_001080515
FAM163B
family with sequence similarity 163, member B
chr1_+_32489426 0.376 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr11_-_62445587 0.376 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr9_+_114376709 0.375 KIAA1958
KIAA1958
chr16_-_29818334 0.368 SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr6_+_29472310 0.368 NM_013936
OR12D2
olfactory receptor, family 12, subfamily D, member 2
chr6_-_11490487 0.358 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr11_-_85146691 0.349 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr1_-_181889070 0.346 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr14_-_93493519 0.343 NM_016150
ASB2
ankyrin repeat and SOCS box containing 2
chrX_+_38096679 0.341 NM_000531
OTC
ornithine carbamoyltransferase
chr8_-_12220195 0.338 NM_001195257
NM_001037804
LOC100133267
DEFB130
defensin, beta 130-like
defensin, beta 130
chr2_-_96320185 0.336 SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr21_-_26345294 0.326


chr19_+_17499064 0.324 FAM129C
family with sequence similarity 129, member C
chr14_-_93919305 0.324 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr15_+_55298908 0.320 NM_207040
TCF12
transcription factor 12
chrX_-_46503540 0.315 SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr3_-_11598829 0.314 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr11_-_56166490 0.314 NM_001002925
OR5AP2
olfactory receptor, family 5, subfamily AP, member 2
chr3_+_23904086 0.310 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr2_-_97775300 0.306 TMEM131
transmembrane protein 131
chr1_+_17817397 0.305 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr10_-_75127559 0.293 NM_001144000
AGAP5
ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
chr8_+_21967008 0.289 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr11_+_46651090 0.288 ATG13
ATG13 autophagy related 13 homolog (S. cerevisiae)
chr5_+_67558217 0.284 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr6_+_36318922 0.282 NM_173676
NM_001145716
PNPLA1

patatin-like phospholipase domain containing 1

chrX_+_46825179 0.278 RGN
regucalcin (senescence marker protein-30)
chr4_-_90978469 0.277 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr14_+_18447521 0.272 NM_001013354
OR11H12
olfactory receptor, family 11, subfamily H, member 12
chr7_+_127020924 0.271 NM_020369
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr3_-_196792274 0.270 NM_001647
APOD
apolipoprotein D
chrX_-_110400406 0.269 NM_014289
CAPN6
calpain 6
chr1_+_24713396 0.266 RCAN3
RCAN family member 3
chr1_+_92405196 0.263 NM_015237
KIAA1107
KIAA1107
chr3_-_10307408 0.261 NM_001134941
NM_016362
GHRL

ghrelin/obestatin prepropeptide

chr1_-_92724181 0.259 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr11_-_4827013 0.259 NM_001004758
OR51S1
olfactory receptor, family 51, subfamily S, member 1
chr19_+_58239802 0.253 NM_001191055
HERV-V2
envelope glycoprotein ENVV2
chr19_+_40224480 0.246 HPN
hepsin
chr9_+_6318348 0.242 NM_001001874
NM_001001875
NM_033516
TPD52L3


tumor protein D52-like 3


chr11_-_58368555 0.242 NM_145016
GLYATL2
glycine-N-acyltransferase-like 2
chr5_+_139856688 0.238 ANKHD1
ankyrin repeat and KH domain containing 1
chr12_+_61240542 0.235 MON2
MON2 homolog (S. cerevisiae)
chr4_-_185921384 0.234 ACSL1
acyl-CoA synthetase long-chain family member 1
chr1_-_120189301 0.230 NM_001047980
NBPF7
neuroblastoma breakpoint family, member 7
chr7_+_104539548 0.230 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr3_+_52788976 0.226 NM_001166435
NM_001166436
ITIH1

inter-alpha (globulin) inhibitor H1

chr7_+_149104063 0.225 NM_198455
SSPO
SCO-spondin homolog (Bos taurus)
chr6_-_42798286 0.223 NM_000322
PRPH2
peripherin 2 (retinal degeneration, slow)
chr7_-_99365178 0.219 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr4_+_14985272 0.218 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr10_+_80743769 0.212 ZMIZ1
zinc finger, MIZ-type containing 1
chr16_+_56286212 0.211 NM_032269
CCDC135
coiled-coil domain containing 135
chr10_-_921694 0.209 NM_015155
LARP4B
La ribonucleoprotein domain family, member 4B
chr10_-_50012058 0.204 NM_001164484
FAM170B
family with sequence similarity 170, member B
chr19_-_44060729 0.203 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr11_-_57752923 0.200 NM_001004471
OR10Q1
olfactory receptor, family 10, subfamily Q, member 1
chr2_-_166638376 0.200 NM_001165963
NM_001165964
NM_006920
SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr6_-_29451042 0.198 NM_030959
OR12D3
olfactory receptor, family 12, subfamily D, member 3
chr6_-_41811916 0.198 NM_001167827
TFEB
transcription factor EB
chr9_+_115303527 0.195 NM_130795
RGS3
regulator of G-protein signaling 3
chr1_-_199613427 0.193 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr19_+_18069596 0.193 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr6_-_29431950 0.193 NM_030876
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr17_+_6599879 0.192 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chrX_-_15593074 0.192 NM_020665
TMEM27
transmembrane protein 27
chr17_-_46479127 0.192 SPAG9
sperm associated antigen 9
chr12_+_27740694 0.189 NM_001029874
REP15
RAB15 effector protein
chr12_+_27511009 0.188 NM_001145010
C12orf70
chromosome 12 open reading frame 70
chr9_+_124355211 0.184 NM_001004457
OR1N2
olfactory receptor, family 1, subfamily N, member 2
chrX_-_2896285 0.184 ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr5_+_173405298 0.183 NM_015980
HMP19
HMP19 protein
chr11_-_11331411 0.183 CSNK2A1P
casein kinase 2, alpha 1 polypeptide pseudogene
chr1_+_33003814 0.181 NM_001198972
NM_001198973
KIAA1522

KIAA1522

chr22_+_23309717 0.180 NM_013430
GGT1
gamma-glutamyltransferase 1
chr10_+_85994788 0.178 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr1_-_151280201 0.178 NM_006945
SPRR2D
small proline-rich protein 2D
chr11_-_4782185 0.175 NM_001005177
OR52R1
olfactory receptor, family 52, subfamily R, member 1
chr11_-_123130435 0.175 NM_001005188
OR6X1
olfactory receptor, family 6, subfamily X, member 1
chr21_+_44844924 0.174 NM_198689
KRTAP10-7
keratin associated protein 10-7
chrX_-_10504852 0.169 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr7_-_92693716 0.169 NM_001039372
HEPACAM2
HEPACAM family member 2
chr1_+_33003847 0.167 KIAA1522
KIAA1522
chr5_-_93102952 0.164 NM_153216
POU5F2
POU domain class 5, transcription factor 2
chr1_-_6343306 0.164 NM_181865
ACOT7
acyl-CoA thioesterase 7
chr6_-_30236667 0.161 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr12_+_55674496 0.161 NM_007264
GPR182
G protein-coupled receptor 182
chr6_+_52159143 0.160 NM_002190
IL17A
interleukin 17A
chr7_+_138695209 0.160 LUC7L2
LUC7-like 2 (S. cerevisiae)
chrX_+_128741562 0.153 NM_018990
SASH3
SAM and SH3 domain containing 3
chr7_+_138695236 0.148 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr1_+_50344550 0.148 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chrX_-_47941142 0.148 NM_021015
NM_175723
SSX5

synovial sarcoma, X breakpoint 5

chr1_+_205328834 0.148 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr4_-_77176163 0.148 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr17_-_16816113 0.147 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr17_-_64568641 0.147 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr22_+_20880112 0.146


chrX_+_102918409 0.142 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr17_+_71975224 0.142 NM_001088
AANAT
aralkylamine N-acetyltransferase
chr5_+_173405343 0.138 HMP19
HMP19 protein
chr15_+_72687765 0.138 NM_003992
CLK3
CDC-like kinase 3
chr2_+_232165818 0.137 NM_152614
C2orf57
chromosome 2 open reading frame 57
chr9_-_35860316 0.137 NM_001004487
OR13J1
olfactory receptor, family 13, subfamily J, member 1
chr6_-_163068788 0.136 PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
chr2_+_232979795 0.133 NM_031313
ALPPL2
alkaline phosphatase, placental-like 2
chr1_-_177106702 0.132 NM_004673
ANGPTL1
angiopoietin-like 1
chrX_-_55037235 0.132 NM_002625
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_+_207926172 0.132 NM_181755
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr19_-_40996040 0.131 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chr16_+_31105579 0.131


chr15_-_79453472 0.130 NM_001080532
TMC3
transmembrane channel-like 3
chr11_+_57547928 0.130 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr3_+_120982020 0.130 NM_003889
NM_033013
NR1I2

nuclear receptor subfamily 1, group I, member 2

chr7_-_2850175 0.129 NM_007353
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr5_+_169749068 0.129


chr7_+_138695241 0.128 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr18_+_53170718 0.128 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr20_-_36191623 0.128 TGM2
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr17_-_64823368 0.125 NM_018672
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr17_+_44642587 0.124 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr1_+_26728846 0.124 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_-_199613406 0.123 TNNT2
troponin T type 2 (cardiac)
chr8_-_20084892 0.123 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr11_-_4902144 0.122 NM_001005237
OR51G1
olfactory receptor, family 51, subfamily G, member 1
chr1_-_202432165 0.121 NM_002256
KISS1
KiSS-1 metastasis-suppressor
chr1_+_100099353 0.121 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chrX_+_102918453 0.119 PLP1
proteolipid protein 1
chr17_-_9864048 0.118 GAS7
growth arrest-specific 7
chr5_-_36036883 0.118 NM_001171873
UGT3A1
UDP glycosyltransferase 3 family, polypeptide A1
chr2_-_55131124 0.117 RTN4
reticulon 4
chr21_-_30614477 0.117 NM_203405
KRTAP26-1
keratin associated protein 26-1
chr1_+_156991133 0.116 NM_001005184
OR6K6
olfactory receptor, family 6, subfamily K, member 6
chr6_+_44302973 0.116 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chr10_-_105427898 0.116 SH3PXD2A
SH3 and PX domains 2A
chr2_-_65013070 0.115 LOC400958
hypothetical LOC400958
chr19_+_61624 0.112 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr7_+_150013716 0.112 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr9_+_102244005 0.111 NM_001198812
C9orf3-TMEFF1
C9orf30
C9orf3-TMEFF1 readthrough
chromosome 9 open reading frame 30
chr3_-_69381995 0.108 FRMD4B
FERM domain containing 4B
chr2_-_55130963 0.108 RTN4
reticulon 4
chr11_-_65182411 0.106 RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr11_+_72658586 0.106 NM_176798
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr7_-_143560850 0.105 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr6_-_41230003 0.104 NM_178174
TREML1
triggering receptor expressed on myeloid cells-like 1
chr6_-_33028790 0.102 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr6_-_163068749 0.102 PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
chr1_+_28134090 0.101 NM_001009568
NM_014474
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr1_+_184532027 0.099 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4




Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.